2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-114750R
    Mebendazole-amine (Standard)
    Mebendazole-amine (Standard) is the analytical standard of Mebendazole-amine. This product is intended for research and analytical applications. Mebendazole-amine is a metabolite of Mebendazole. Mebendazole is a broad-spectrum benzimidazole anti-helminthic agent.
    Mebendazole-amine (Standard)
  • HY-A0154R
    Deslanoside (Standard)
    Deslanoside (Standard) is the analytical standard of Deslanoside. This product is intended for research and analytical applications. Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations .
    Deslanoside (Standard)
  • HY-171043
    3-Hydroxy desalkylgidazepam
    3-Hydroxy desalkylgidazepam (compound 2) is the active metabolite of Gidazepam (HY-U00315) and Desalkylgidazepam (HY-W634748).
    3-Hydroxy desalkylgidazepam
  • HY-W717548
    Safinamide acid
    Safinamide acid (Compound Imp-E) is the metabolite of Safinamide (HY-70057). Safinamide acid can be formed by hydrolysis of Safinamide intermediate under alkaline or acidic conditions. Safinamide acid is utilized to monitor process-related impurities and degradation products in safinamide samples.
    Safinamide acid
  • HY-W335576
    3-(Methylphosphinico)propionic acid
    3-(Methylphosphinico)propionic acid serves as a metabolite of the pesticide glufosinate ammonium.
    3-(Methylphosphinico)propionic acid
  • HY-126194
    Tolcapone 3-β-D-glucuronide
    Tolcapone 3-β-D-glucuronide (Ro 61-1448) is an O-methyl metabolite and the glucuronide metabolite of Tolcapone (Ro 40-7592; HY-17406). Tolcapone 3-β-D-glucuronide is pharmacologically inactive.
    Tolcapone 3-β-D-glucuronide
  • HY-123001
    Nomelidine
    Nomelidine is the metabolite of Zimelidine (HY-118835), that exhibits antidepressant and analgesic properties.
    Nomelidine
  • HY-150333
    MMB-ICA
    MMB-ICA is a metabolite of MMB-CHMICA.
    MMB-ICA
  • HY-W741106
    5-Hydroxybuspirone
    5-Hydroxybuspirone is a metabolite of the anti-anxiety agent Buspirone (HY-B1115A).
    5-Hydroxybuspirone
  • HY-124041
    p-Hydroxybestatin
    p-Hydroxybestatin is an active metabolite of Bestatinc (HY-B0134) that can be found in serum from muscular dystrophic patients and from healthy subjects dosed with Bestatin.
    p-Hydroxybestatin
  • HY-100583AR
    (±)-Equol (Standard)
    (±)-Equol (Standard)
  • HY-134999
    10-Hydroxywarfarin
    10-Hydroxywarfarin, a metabolite of (R)-(+)-Warfarin (HY-W015998 ), is a CYP2C9 and vitamin K epoxide reductase complex 1 (VKOR) inhibitor with IC50s of 1.6 µM and 80 ng/mL, respectively.
    10-Hydroxywarfarin
  • HY-W011055A
    6-Hydroxycortisol
    6-Hydroxycortisol is the metabolite of Cortisol (HY-N0583). 6-Hydroxycortisol can be used as an indicator of Cortisol metabolism.
    6-Hydroxycortisol
  • HY-118025
    (±)-2-Oxo clopidogrel
    		99.67%
    (±)-2-Oxo clopidogrel is a metabolite of the antiplatelet agent Clopidogrel (HY-15283).
    (±)-2-Oxo clopidogrel
  • HY-111811
    Homomangiferin
    Homomangiferin is mangiferin monomethyl ether. Homomangiferin has important medicinal properties and is widely used to relieve many symptoms, for example coughing and asthma.
    Homomangiferin
  • HY-B1986R
    p,p'-DDE (Standard)
    p,p'-DDE (Standard) is the analytical standard of p,p'-DDE. This product is intended for research and analytical applications. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM.
    p,p'-DDE (Standard)
  • HY-W014993S1
    1,3-Dimethyluric acid-dsub>3
    1,3-Dimethyluric acid-d3 is deuterated labeled 1,3-Dimethyluric acid (HY-W014993). 1,3-Dimethyluric acid is a product of theophylline metabolism in man. 1,3-Dimethyluric acid is one of the purine components in urinary calculi.
    1,3-Dimethyluric acid-dsub>3</sub>
  • HY-116074
    FUB-PB-22 3-carboxyindole metabolite
    FUB-PB-22 3-carboxyindole metabolite is the main metabolite of FDU-PB-22 and FUB-PB-22.
    FUB-PB-22 3-carboxyindole metabolite
  • HY-W709579
    AB-CHMINACA metabolite M5A
    		Control
    AB-CHMINACA metabolite M5A is a metabolite of AB-CHMINACA in the liver.
    AB-CHMINACA metabolite M5A
  • HY-169045
    (±)13,14-EDT
    		Control
    (±)13,14-EDT is an oxylipin and a metabolite of Adrenic acid (HY-W013215) formed via the cytochrome P450 (CYP) pathway.
    (±)13,14-EDT
Cat. No. Product Name / Synonyms Application Reactivity